L469405 Chemical Structure

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Product Description

Catalogue NumberL469405
Chemical NameLoganin
Synonyms(1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester; (-)-Loganin; Loganoside; (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester; 7-Hydroxy-6-desoxyverbenalin; NSC 606403;
CAS Number18524-94-2
Molecular FormulaC17H26O10
AppearanceWhite to Pale Yellow Solid
Melting Point>200°C (dec.)
Molecular Weight390.38
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityAcetonitrile (Very Slightly, Heated), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
ApplicationsAn iridoid glycoside that exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. A potential anti-amnesic agent.
ReferencesYamabe, N. et al.: Eur. J. Pharmmacol., 648, 179 (2010); de Carman Recio, M. et al.: Planta Medica, 3, 232 (1994); Kwon, S. et al.: Eur. J. Pharmacol., 619, 44 (2009);