L469400 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 80.000.0
2.5mg
$ 130.000.0
10mg
$ 375.000.0
25mg
$ 745.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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L469400

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Product Description

Catalogue NumberL469400
Chemical Name(S)-Lofexidine
Synonyms2-[(1S)-1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole; (-)-Lofexidine; Dexlofexidine;
CAS Number81447-79-2
Alternate CAS #87858-98-8-for HCl
Molecular FormulaC11H12Cl2N2O
AppearanceWhite to Off-White Solid
Melting Point104-107°C
Molecular Weight259.13
Storage-20°C Freezer
SolubilityChloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsThe S-enantiomer of Lofexidine. α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
ReferencesVelly, J., et al.: J. Pharmacol., 8, 351 (1977), Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979), Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980),