L469053 Chemical Structure

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2.5mg
$ 145.000.0
25mg
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Exact Weight Packaging
$ 95.000.0
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L469053

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Product Description

Catalogue NumberL469053
Chemical Name(+/-)-Lisofylline-d6
Synonyms3,7-Dihydro-1-(5-hydroxyhexyl-d6)-3,7-dimethyl-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl-d6)theobromine; (+/-)-1-(5-Hydroxyhexyl-d6)-3,7-dimethyl xanthine; BL 194-d6; Pentoxifylline-d6 Alcohol;
CAS Number1185995-47-4
Alternate CAS #6493-06-7-unlabelled
Molecular FormulaC13H14D6N4O3
Molecular Weight286.36
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.
ReferencesClarke, E., et al.: Cancer Res., et al.: 56, 105 (1996), Itani, S., et al.: Metabolism, 50, 553 (2001), Itani, S., et al.: Diabetes, 51, 2005 (2002), Yu, C., et al.: J. Biol. Chem., 277, 50230 (2002),