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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 245.00 | 0.0 | |
| 10mg | $ 1940.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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L469052
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Product Description
| Catalogue Number | L469052 |
| Chemical Name | (+/-)-Lisofylline-d6 |
| Synonyms | 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-(dimethyl-d6)-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl)theobromine-d6; (+/-)-1-(5-Hydroxyhexyl)-3,7-(dimethyl-d6) xanthine; BL 194-d6; Pentoxifylline-d6 Alcohol; Hydroxypentoxifylline-d6 |
| CAS Number | 1185995-26-9 |
| Alternate CAS # | 6493-06-7-unlabelled |
| Molecular Formula | C₁₃H₁₄D₆N₄O₃ |
| Appearance | White to Off-White Solid |
| Melting Point | 125-127°C |
| Molecular Weight | 286.36 |
| Storage | -20°C Freezer |
| Solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| Category | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | A major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig. |
| References | Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996), Itani, S., et al.: Metabolism, 50, 553 (2001), Itani, S., et al.: Diabetes, 51, 2005 (2002), Yu, C., et al.: J. Biol. Chem., 277, 50230 (2002), |