L469050 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 70.000.0
25mg
$ 105.000.0
50mg
$ 205.000.0
100mg
$ 360.000.0
250mg
$ 810.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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L469050

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Product Description

Catalogue NumberL469050
Chemical Name(+/-)-Lisofylline
Synonyms3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl)theobromine; (+/-)-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine; BL 194; Pentoxifylline Alcohol; Hydroxy pentoxifylline
CAS Number6493-06-7
Molecular FormulaC₁₃H₂₀N₄O₃
AppearanceWhite Solid
Melting Point123-125°C
Molecular Weight280.32
StorageRefrigerator
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA major oxidative metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.
ReferencesClarke, E., et al.: Cancer Res., et al.: 56, 105 (1996), Itani, S., et al.: Metabolism, 50, 553 (2001), Itani, S., et al.: Diabetes, 51, 2005 (2002), Yu, C., et al.: J. Biol. Chem., 277, 50230 (2002),