All Products are stable to be shipped at room temperature, unless otherwise specified.
| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 10mg | $ 8785.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
Product successfully added to cart.
- Request another packsize ? Click here.
- Inventory Status : Currently Back Ordered - Please Request Lead Time
- Ships On :
L469022
Bulk Order Request for L469022
Product Description
| Catalogue Number | L469022 |
| Chemical Name | Linsitinib-d3 |
| Synonyms | cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-(methyl-d3)cyclobutanol; OSI 906-d3; OSI 906AA-d3; |
| Alternate CAS # | unlabelled: 867160-71-2 |
| Molecular Formula | C26H20D3N5O |
| Molecular Weight | 424.51 |
| Category | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Labelled Linsitinib (L469020). Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent. |
| References | Mulvihill, M.M.J. et al.: Fut. Med. Chem., 1, 1153 (2009); Flanigan, S.A. et al.: Clin. Cancer Res., 16, 5436 (2010); McKinley, E.T. et al.: Clin. Cancer Res., 17, 3332 (2011); |