Levothyroxine N-Methylamide


Catalogue number: L378050
Chemical name: Levothyroxine N-Methylamide
Synonyms: (S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide
Impurity:
CAS Number: NA
Alternate CAS #: NA
Molecular form.: C₁₆H₁₄I₄N₂O₃
Appearance: Beige Solid
Melting Point: >125°C (dec.)
Mol. Weight: 789.91
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Impurities
Boiling Point: No Data Available
Applications: Levothyroxine N-Methylamide is an impurity of Thyroxine (T425600), one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
Dangerous Goods Info: NA
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: L378050.pdf
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