LEE011 Succinate

Catalogue number: L321000
Chemical name: LEE011 Succinate
Synonyms: 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide Succinate
CAS Number: 1374639-75-4
Possible CAS #: NA
Molecular form.: C₂₇H₃₆N₈O₅
Appearance: Pale Beige Solid
Melting Point: >160ºC (dec.)
Mol. Weight: 552.63
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors
Boiling Point: No Data Available
Applications: LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models.
Dangerous Goods Info: NA
Peer Review Product Citations:
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Order Product

  Pack size Price(USD)
2.5mg $150.00
50mg $1125.00
  Pack size Price(USD)
10mg $275.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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