Lamivudine (S)-Sulfoxide

Catalogue number: L172470
Chemical name: Lamivudine (S)-Sulfoxide
Synonyms: Lamivudine (S)-S-Oxide; 4-Amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,3α,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3α,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; GI 138868X; Lamivudine EP Impurity G
Impurity: Lamivudine EP Impurity G
CAS Number: 160552-55-6
Possible CAS #: NA
Molecular form.: C₈H₁₁N₃O₄S
Appearance: White Solid
Melting Point: >220°C (dec.)
Mol. Weight: 245.26
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Lamivudine (S)-Sulfoxide (Lamivudine EP Impurity G) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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