L101000 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
0.25mg
$ 145.000.0
1mg
$ 295.000.0
2mg
$ 360.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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L101000

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Product Description

Catalogue NumberL101000
Chemical Name(+)-Lactacystin
SynonymsN-Acetyl-S-[(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-D-prolyl]-L-cysteine; Lactacystin;
CAS Number133343-34-7
Molecular FormulaC₁₅H₂₄N₂O₇S
AppearanceWhite to Pale Brown Solid
Melting Point>180°C (dec.)
Molecular Weight376.43
Storage-20°C Freezer
SolubilityDMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated)
Category Standards; Enzyme Activators and Inhibitors;
ApplicationsA selective and potent inhibitor of proteasome-mediated degradation of ubiquitin-tagged proteins. A Streptomyces metabolite that acts as a highly specific inhibitor of the 20S proteasome (MCP: multicatalytic proteinase complex).
ReferencesFenteany, G., et al.: Science, 268, 726 (1995), Fenteany, G., et al.: Proc. Natl. Acad. Sci. USA, 91, 3358 (1994),