Abacavir (1.0 mg/mL in Methanol)


Catalogue Number: KIT7770
Chemical Name: Abacavir (1.0 mg/mL in Methanol)
Synonyms: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; 1592U89; ABC; Abacavir API;
CAS Number: 136470-78-5
Molecular Formula: C₁₄H₁₈N₆O
Appearance: Clear Colourless Solution
Melting Point: N/A
Molecular Weight: 286.33
Storage: -20°C Freezer
Solubility: Methanol
Applications: Abacavir (Abacavir API) is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
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