Catalogue number: K660400
Chemical name: KU-0058948
Synonyms: 4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone; KU 0058948; KU0058948; 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine;
CAS Number: 763111-49-5
Alternate CAS #: NA
Molecular form.: C₂₁H₂₁FN₄O₂
Appearance: Pale Yellow to Yellowish Beige Solid
Melting Point: >150°C (dec.)
Mol. Weight: 380.42
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Apoptosis, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 is a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: K660400.pdf
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  Pack size Price(USD)
2.5mg $140.00
100mg $1975.00
  Pack size Price(USD)
10mg $225.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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