K648500 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
25mg
$ 195.000.0
250mg
$ 1475.000.0
Exact Weight Packaging
$ 145.000.0
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  • Ships On : 4/13/2023
K648500

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Product Description

Catalogue NumberK648500
Chemical NameKML-29
Synonyms4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic Acid 2,2,2-Trifluoro-1-(trifluoromethyl)ethyl Ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(Bis(benzo[d][1,3]dioxol-5-yl)(hydroxy)methyl)piperidine-1-carboxylate; KML29;
CAS Number1380424-42-9
Molecular FormulaC24H21F6NO7
AppearanceWhite to Off-White Solid
Melting Point204-206°C
Molecular Weight549.42
Storage-20°C Freezer
SolubilityChloroform (Slightly, Heated, Sonicated), Methanol (Slightly, Heated)
Category Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsKML-29 is an extremely specific monoacylglycerol lipase (MAGL) inhibitor. KML-2 should be useful to distinguish between actions of 2-arachidonoyl glycerol (an endogenous ligand of cannabinoid receptors that is deactivated by MAGL) and anandamide, another endocannabinoid.
ReferencesUeda, N. et al.: Chem. Biol., 19, 545 (2012);