Catalogue Number: K450000
Chemical Name: Kifunensine
Synonyms: [5R-(5α,6β,7α,8α,8aα)]-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione; (+)-Kifunensine; FR 900494
CAS Number: 109944-15-2
Molecular Formula: C₈H₁₂N₂O₆
Appearance: White to Off-White Solid
Melting Point: >208°C (dec.)
Molecular Weight: 232.19
Storage: -20°C Freezer
Solubility: Water (Slightly, Heated)
Stability: Desiccate and Store at -20°C
Category: Inhibitors, Glycosidase Inhibitors,
Applications: Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis. When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin. Ph

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: K450000.pdf
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  Pack size Price(USD)
1mg $50.00
10mg $190.00
50mg $690.00
  Pack size Price(USD)
2.5mg $70.00
25mg $360.00

Exact Weight Packaging ($75(USD) / Vial)
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