K432105 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 95.000.0
2.5mg
$ 225.000.0
mg5
$ 415.000.0
10mg
$ 815.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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K432105

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Product Description

Catalogue NumberK432105
Chemical Name(+)-cis-Khellactone
Synonyms(9R,​10R)​-9,​10-​Dihydro-​9,​10-​dihydroxy-​8,​8-​dimethyl-2H,​8H-​Benzo[1,​2-​b:3,​4-​b']​dipyran-​2-​one; (9R-cis)-9,10-Dihydro-9,10-dihydroxy-8,8-dimethyl-2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one; 9,10-Dihydro-9,10-dihydroxy-8,8-dimethyl-2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one Stereoisomer; (3'R,4'R)-(+)-cis-Khellactone; cis-(+)-Khellactone
CAS Number24144-61-4
Molecular FormulaC14H14O5
AppearanceTan Powder
Molecular Weight262.26
SolubilityEthyl Acetate, THF
Category Standards; Chiral Molecules;
Applications(+)-cis-Khellactone is an intermediate in the synthesis of rac Samidin (S110500), a potent vasodilatory agent isolated from Ammi visnaga. cis-Khellactone is a coumarin agent which displays potential P-glycoprotein modulation activity. Antiplatelet aggregation.
ReferencesOkuyama, T., et al.: Planta Med., 42, 89 (1981); Matsuda, H., et al.: Chem. Pharm. Bull, 48, 1429 (2000); Abad, M., et al.: Pharm. Pharmacol., 53, 1163 (2001); Jong, T. et al: J. Nat. Prod., 55, 1396 (1992); Shen, X. et al.: J. Pharm. Pharmacol., 64, 90 (2012);