K186025 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 125.000.0
25mg
$ 230.000.0
100mg
$ 680.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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K186025

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Product Description

Catalogue NumberK186025
Chemical Name(-)-Ketoconazole
Synonyms1-Acetyl-4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; (2S-cis)-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; 1-[4-[4-[[(2S,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]ethanone; (-)-(2S,4R)-Ketoconazole; COR 003; Levoketoconazole; 1-[4-[4-[[(2S,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]-ethanone
CAS Number142128-57-2
Molecular FormulaC₂₆H₂₈Cl₂N₄O₄
Molecular Weight531.43
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(-)-Ketoconazole along with other Ketoconazle stereoisomers can be used in pharmacological activity and biological study for inducing CYP4501A1 in human and mouse hepatoma. (-)-Ketoconazole has adverse effect as impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesAnwar-Mohamed, A., et al.: J. Pharm. Sci., 105, 1318-1326 (2016); Grycova, A., et al.: Toxicol. Lett., 239, 67-72 (2015):