(-)-Ketoconazole


Catalogue number: K186025
Chemical name: (-)-Ketoconazole
Synonyms: 1-Acetyl-4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; (2S-cis)-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; 1-[4-[4-[[(2S,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]ethanone; (-)-(2S,4R)-Ketoconazole; COR 003; Levoketoconazole; 1-[4-[4-[[(2S,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]-ethanone
Impurity:
CAS Number: 142128-57-2
Alternate CAS #: NA
Molecular form.: C₂₆H₂₈Cl₂N₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 531.43
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (-)-Ketoconazole along with other Ketoconazle stereoisomers can be used in pharmacological activity and biological study for inducing CYP4501A1 in human and mouse hepatoma. (-)-Ketoconazole has adverse effect as impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor.
Dangerous Goods Info: NA
References:

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