K135015 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 95.000.0
100mg
$ 745.000.0
250mg
$ 1485.000.0
Exact Weight Packaging
$ 95.000.0
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  • Ships On : 2/10/2022
K135015

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Product Description

Catalogue NumberK135015
Chemical Name(-)-α-Kainic Acid Lithium Salt
SynonymsLithium 2-((2S,3S,4S)-2-carboxy-4-(prop-1-en-2-yl)pyrrolidin-3-yl)acetate;
Alternate CAS #Free Base: 487-79-6
Molecular FormulaC₁₀H₁₄LiNO₄
AppearanceWhite to Off-White Solid
Melting Point>250°C (dec.)
Molecular Weight219.16
StorageHygroscopic, Refrigerator, under inert atmosphere
SolubilityWater
Category Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(-)-α-Kainic Acid Lithium Salt is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.
ReferencesWacker, D.A., et al.: Synlett, 503 (1997), Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)’