All Products are stable to be shipped at room temperature, unless otherwise specified.
| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 10mg | $ 95.00 | 0.0 | |
| 100mg | $ 745.00 | 0.0 | |
| 250mg | $ 1485.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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- Inventory Status : Pending QC
- Ships On : 2/10/2022
K135015
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Product Description
| Catalogue Number | K135015 |
| Chemical Name | (-)-α-Kainic Acid Lithium Salt |
| Synonyms | Lithium 2-((2S,3S,4S)-2-carboxy-4-(prop-1-en-2-yl)pyrrolidin-3-yl)acetate; |
| Alternate CAS # | Free Base: 487-79-6 |
| Molecular Formula | C₁₀H₁₄LiNO₄ |
| Appearance | White to Off-White Solid |
| Melting Point | >250°C (dec.) |
| Molecular Weight | 219.16 |
| Storage | Hygroscopic, Refrigerator, under inert atmosphere |
| Solubility | Water |
| Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | (-)-α-Kainic Acid Lithium Salt is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus. |
| References | Wacker, D.A., et al.: Synlett, 503 (1997), Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)’ |