(S)-Hydroxy Des(boric Acid) Bortezomib

Catalogue number: H935905
Chemical name: (S)-Hydroxy Des(boric Acid) Bortezomib
Synonyms: N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide; N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazinecarboxamide;
Impurity:
CAS Number: 289472-81-7
Possible CAS #: NA
Molecular form.: C₁₉H₂₄N₄O₃
Appearance: White to Off-White Solid
Melting Point: 125-127°C
Mol. Weight: 356.42
Storage: -20°C Freezer
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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  Pack size Price(USD)
0.5mg $150.00
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  Pack size Price(USD)
5mg $1200.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   Pending QC



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