H826006 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
0.25mg
$ 165.000.0
1mg
$ 765.000.0
2.5mg
$ 1320.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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H826006

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Product Description

Catalogue NumberH826006
Chemical Name(-)-Huperzine A-d7 major (>90%)
Synonyms(5R,9R,11E)-5-Amino-11-(ethylidene-2,2,2-d3)-5,6,9,10-tetrahydro-7-(methyl-d3-)-5,9-methanocycloocta[b]pyridin-2(1H)-one-d7 ;
Alternate CAS #102518-79-6
Molecular FormulaC₁₅H₁₁D₇N₂O
AppearanceLight Brown to Brown Solid
Molecular Weight249.36
StorageRefrigerator, under inert atmosphere
SolubilityChloroform (Slightly), Methanol (Slightly)
Category Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(-)-Huperzine A-d7 major (>90%) is the labelled form of (-)-Huperzine A (H826000), a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer’s disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain.
ReferencesWang, Y.-E., et al.: Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al.: Neuroreport, 8, 963 (1997)