Catalogue number: G304500
Chemical name: Geldanamycin
Synonyms: 9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-Carbamate; (+)-Geldanamycin; NSC 122750; NSC 212518;
CAS Number: 30562-34-6
Possible CAS #: NA
Molecular form.: C₂₉H₄₀N₂O₉
Appearance: Yellow to Orange Solid
Melting Point: 236-240˚C
Mol. Weight: 560.64
Storage: -20°C Freezer
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines. It binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
1mg $45.00
5mg $95.00
25mg $345.00
  Pack size Price(USD)
2.5mg $65.00
10mg $150.00
50mg $625.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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