F844570 Chemical Structure

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Product Description

Catalogue NumberF844570
Chemical NameN-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-(((benzyloxy)carbonyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)acetyl)glycine
SynonymsN-​[[1,​6-​Dihydro-​6-​oxo-​2-​[[(phenylmethoxy)​carbonyl]​amino]​-​9H-​purin-​9-​yl]​acetyl]​-​N-​[2-​[[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​amino]​ethyl]​glycine; Guanosine NCBZ AA-FMOC
CAS Number169397-01-7
Alternate CAS #73-40-5
Molecular FormulaC34H31N7O8
Molecular Weight665.65
Category Building Blocks; Nucleic Acid; Amino Acids; Molecular Biology; Amino Acids/Peptides; Nucleic Acids;
ApplicationsN-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-(((benzyloxy)carbonyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)acetyl)glycine is a peptide nucleic acid (PNA) that can be useful in the synthesis of pyrrolidine-​based peptide nucleic acid that contains tertiary amines in the main chain and examining its internalization into cells. It can also be useful in the synthesis of cyclic PNA and PNA-DNA chimeras and dioxime-​peptide nucleic acids.
ReferencesKitamatsu, M., et al.: Chem. Lett., 35, 300 (2006); Moggio, L., et al.: Org. Lett., 8, 2015 (2006); Mokhir, A., et al.: Bioorg. Med. Chem. Lett., 14, 2927 (2004)