F510000 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 105.000.0
5mg
$ 145.000.0
10mg
$ 200.000.0
25mg
$ 455.000.0
50mg
$ 855.000.0
100mg
$ 1545.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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Product Description

Catalogue NumberF510000
Chemical Name2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate
SynonymsMethanesulfonothioic Acid S-[3-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-3-oxopropyl] Ester; MTS-4-Fluorescein
CAS Number351330-42-2
Molecular FormulaC₂₄H₁₉NO₈S₂
AppearanceYellow to Pale Orange to Red Solid
Melting Point>162°C dec.
Molecular Weight513.54
Storage-20°C, Inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Fluorescent Reagents; Sulfhydryl Active Reagents;
ApplicationsA thiol specific fluorescent probe useful for ion channel and protein topology research. The recently available MTS-fluorophores may find application in the real-time monitoring of conformational changes, since fluorophores coupled to introduced cysteines can change their fluorescence during a conformational change. Fluorescence lifetime may also yield information regarding distances and molecular motion in a protein molecule.Fluorescence: max. Abs. 492nm; max. Em. 515nm; e x 10-3: 75
ReferencesMannuzzu, L.M., et al.: Science, 271, 213 (1996), Goulett, C.C., et al.: JBC, 273, 45, 30012 (1998), Adams, C.M., et al.: JBC, 273, 46, 30204 (1998)