Catalogue number: F336500
Chemical name: FIIN-1
Synonyms: N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; FGFR Irreversible Inhibitor 1; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide;
CAS Number: 1256152-35-8
Possible CAS #: NA
Molecular form.: C₃₂H₃₉Cl₂N₇O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 656.6
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1 (1).The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.
Dangerous Goods Info: NA
Peer Review Product Citations:
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