F335410 Chemical Structure

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2.5mg
$ 185.000.0
25mg
$ 1405.000.0
Exact Weight Packaging
$ 145.000.0
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F335410

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Product Description

Catalogue NumberF335410
Chemical Name3’’’,5’’’-Dideshydroxy-3’’’,5’’’-dimethoxy Fidaxomicin
Synonyms(3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dimethoxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one;
CAS Number185248-68-4
Molecular FormulaC₅₄H₇₈Cl₂O₁₈
AppearanceWhite to Off-White Solid
Melting Point130 - 134°C
Molecular Weight1086.09
Storage-20°C, Inert atmosphere
SolubilityMethanol (Slightly)
Category Research Tools; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications3тАЩтАЩтАЩ,5тАЩтАЩтАЩ-Dideshydroxy-3тАЩтАЩтАЩ,5тАЩтАЩтАЩ-dimethoxy Fidaxomicin is a derivative of Fidaxomicin (F335400), a nonabsorbed macrocyclic antibiotic, and is also the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years.
ReferencesBabakhani, F., et al.: Clin. Infect. Dis., 55, S162 (2012); Venugopal, A., et al.: Clin. Infect. Dis., 54, 568 (2012)