F335402 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
0.5mg
$ 325.000.0
5mg
$ 2890.000.0
25mg
$ 11230.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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  • Ships On : 2/28/2023
F335402

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Product Description

Catalogue NumberF335402
Chemical NameFidaxomicin-D7
Synonyms(3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one-D7;
CAS Number2143934-06-7
Alternate CAS #Unlabelled: 873857-62-6
Molecular FormulaC₅₂H₆₇D₇Cl₂O₁₈
AppearanceOff-White Solid
Melting Point>123°C (dec.)
Molecular Weight1065.08
Storage4°C
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
ApplicationsFidaxomicin-D7 is a labelled analogue of Fidaxomicin (F335400). Fidaxomicin is a nonabsorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen.
ReferencesBabakhani, F., et al.: Clin. Infect. Dis., 55, S162 (2012); Venugopal, A., et al.: Clin. Infect. Dis., 54, 568 (2012)