F335402 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
0.5mg
$ 305.000.0
5mg
$ 2725.000.0
mg25
$ 10590.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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  • Ships On : 7/12/2022
F335402

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Product Description

Catalogue NumberF335402
Chemical NameFidaxomicin-D7
Synonyms(3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one-D7; Clostomicin B1-D7; Dificid-D7; Dificlir-D7; Fidaxomicin-D7; Fidaxomycin-D7; Lipiarmicin-D7; Lipiarmycin-D7; Lipiarmycin-D7 A 3; OPT 80-D7; PAR 01-D7; PAR 101-D7; R-Tiacumicin B-D7; Tiacumicin B-D7
CAS Number2143934-06-7
Alternate CAS #Unlabelled: 873857-62-6
Molecular FormulaC52H67D7Cl2O18
AppearanceOff-White Solid
Melting Point>123°C (dec.)
Molecular Weight1065.08
StorageRefrigerator
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
ApplicationsFidaxomicin-D7 is a labelled analogue of Fidaxomicin (F335400). Fidaxomicin is a nonabsorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen.
ReferencesBabakhani, F., et al.: Clin. Infect. Dis., 55, S162 (2012); Venugopal, A., et al.: Clin. Infect. Dis., 54, 568 (2012)