F102360 Chemical Structure

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100mg
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250mg
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F102360

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Product Description

Catalogue NumberF102360
Chemical Name(+)-Fangchinoline
Synonyms(4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol; (+)-Fangchinoline; (+)-Limacine; [4aS-(4aR*,16aR*)]-3,4,4a,5,16a,17,18,19-Octahydro-12,21,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol; 7-O-Demethyltetrandrine; Hanfangchin B; NSC 77036
CAS Number436-77-1
Molecular FormulaC₃₇H₄₀N₂O₆
Molecular Weight608.72
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(+)-Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
ReferencesXing, Z. et al.: Chem. Pharm. Bull., 59, 1476 (2011); Wan, Z. et al.: PLoS One. 7, e39225 (2012);