E892670 Chemical Structure

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1mg
$ 175.000.0
2.5mg
$ 290.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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E892670

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Product Description

Catalogue NumberE892670
Chemical NameN-​[1-​[3-​(4-Ethoxyphenyl)​-​3,​4-​dihydro-​4-​oxopyrido[2,​3-​d]​pyrimidin-​2-​yl]​ethyl]​-​4-​fluoro-​N-​(3-​pyridinylmethyl)​-​3-​(trifluoromethyl)​-benzeneacetamide
Synonyms(±)​-​NBI 74330
CAS Number473722-68-8
Molecular FormulaC32H27F4N5O3
Molecular Weight605.58
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsN-​[1-​[3-​(4-Ethoxyphenyl)​-​3,​4-​dihydro-​4-​oxopyrido[2,​3-​d]​pyrimidin-​2-​yl]​ethyl]​-​4-​fluoro-​N-​(3-​pyridinylmethyl)​-​3-​(trifluoromethyl)​-benzeneacetamide is a potent and selective CXCR3 antagonist. CXCR3 is a chemokine receptor involved in many inflammatory diseases including rheumatoid arthritis, multiple sclerosis and psoriasis.
ReferencesVerzijl, D., et al.: J Pharmacol Exp Ther. 325, 544 (2008); Storelli, S., et al.: Arch Pharm (Weinheim). 340, 281 (2007)