Catalogue number: E588830
Chemical name: 8-Epitacrolimus
Synonyms: (-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8R*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone; Tacrolimus 8-Epimer
CAS Number: 129212-35-7
Alternate CAS #: NA
Molecular form.: C₄₄H₆₉NO₁₂
Appearance: Pale Yellow Solid
Melting Point: 173-177°C
Mol. Weight: 804.02
Storage: -20˚C Freezer, Under Inert Atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: 8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus (F370000).
Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: E588830.pdf
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0.5mg $250.00
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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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