E555258 Chemical Structure

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1mg
$ 190.000.0
10mg
$ 1440.000.0
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E555258

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Product Description

Catalogue NumberE555258
Chemical NameEnalapril-d3 Hydrochloride
Synonyms(S)-1-[N-[1-(Ethoxycarbonxyl)-3-phenylpropyl]-L-alanyl]-L-proline-d3 Hydrochloride
Alternate CAS #Free base: 1356847-94-3
Molecular FormulaC₂₀H₂₅D₃N₂O₅ • HC l
AppearanceWhite to Pale Yellow Solid
Melting Point>90°C (dec.)
Molecular Weight379.47 + 36.46
Storage-20°C, Hygroscopic
SolubilityDMSO (Slightly), Methanol (Slightly)
StabilityHygroscopic
Category Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsEnalapril-d3 Hydrochloride is the hydrochloride salt of Enalapril-d3 (E555253), which is the labeled version of Enalapril (E555403), an antihypertensive that is also an angiotensin-converting enzyme (ACE) inhibitor.
ReferencesGross, M., et al.: J. Pharmacol. Exp. Ther., 216, 552 (1980), Gomez, H.J., et al.: J. Cardiovasc. Pharmacol., 15, Suppl. 3, S26-S29, (1990), MacFadyen, J., et al.: Clin. Pharmacokinet., 25, 274 (1993), Malini, P.L.: Adv. Ther., 10, 253 (1993)