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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
10mg | $ 130.00 | 0.0 | |
100mg | $ 990.00 | 0.0 | |
mg500 | $ 1980.00 | 0.0 | |
Exact Weight Packaging | $ 95.00 | 0.0 | |
Total | $ 0.0 |
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D679200
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Product Description
Catalogue Number | D679200 |
Chemical Name | Droloxifene Citrate |
Synonyms | 3-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 2-Hydroxy-1,2,3-propanetricarboxylate (1:1); (E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol 2-Hydroxy-1,2,3-propanetricarboxylate (1:1) (salt) |
CAS Number | 97752-20-0 |
Alternate CAS # | Free Base: 82413-20-5 |
Molecular Formula | C32H37NO9 |
Appearance | White to Off-White Solid |
Melting Point | >143°C (dec.) |
Molecular Weight | 579.64 |
Storage | Amber Vial, -20°C Freezer |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Stability | Light Sensitive |
Category | Research Tools; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Droloxifene is a non-steroidal anti-oestrogen that is structurally related to Tamoxifen (T006000), a drug used to prevent the occurrence of breast cancer in postmenopausal women. Droloxifene has a very high binding affinity to estrogen receptors and is used, similarly to Tamoxifen, to prevent and treat breast cancer. |
References | Coombes, R., et al.: New Engl. J. Med., 350, 1081 (2004); Geisler, J., et al.: J. Ster. Biochem. Mol. Biol., 55, 193 (1995); Hasmann, M., et al.: Cancer Lett., 84, 101 (1994); Powles, T., et al.: Lancet 352, 98 (1998) |