D596825 Chemical Structure

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10mg
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50mg
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100mg
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D596825

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Product Description

Catalogue NumberD596825
Chemical NameDiltiazem Sulfone N-Oxide
Synonyms2-((2S,3S)-3-Acetoxy-2-(4-methoxyphenyl)-1,1-dioxido-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-N,N-dimethylethanamine Oxide
Molecular FormulaC22H26N2O7S
Molecular Weight462.52
Category Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;
ApplicationsDiltiazem Sulphone N-Oxide is an analogue of Diltiazem (D460620), a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV), and it can be administered in adjunctive therapy to treat tachycardia and tachyarrhythmias in patients with hyperthyroidism if beta-blockers cannot be used
ReferencesSato, et al.: Arzneim.-Forsch., 21, 1338 (1971); Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998); Hansson, L., et al.: Lancet, 356, 359 (2000); Fihn, D., et. al.: Circulation, 126, 354 (2012)