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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
10mg | $ 170.00 | 0.0 | |
50mg | $ 790.00 | 0.0 | |
100mg | $ 1360.00 | 0.0 | |
Exact Weight Packaging | $ 95.00 | 0.0 | |
Total | $ 0.0 |
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D596825
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Product Description
Catalogue Number | D596825 |
Chemical Name | Diltiazem Sulfone N-Oxide |
Synonyms | 2-((2S,3S)-3-Acetoxy-2-(4-methoxyphenyl)-1,1-dioxido-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-N,N-dimethylethanamine Oxide |
Molecular Formula | C₂₂H₂₆N₂O₇S |
Molecular Weight | 462.52 |
Category | Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites; |
Applications | Diltiazem Sulphone N-Oxide is an analogue of Diltiazem (D460620), a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV), and it can be administered in adjunctive therapy to treat tachycardia and tachyarrhythmias in patients with hyperthyroidism if beta-blockers cannot be used |
References | Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971);Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998);Hansson, L., et al.: Lancet, 356, 359 (2000);Fihn, D., et. al.: Circulation, 126, 354 (2012) |