Catalogue number: D534250
Chemical name: Doramapimod
Synonyms: N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N’-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea; BIRB 796BS; Birb 796;
CAS Number: 285983-48-4
Possible CAS #: NA
Molecular form.: C₃₁H₃₇N₅O₃
Appearance: Pale Beige Solid
Melting Point: >136°C (dec.)
Mol. Weight: 527.66
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: Doramapimod is a highly potent inhibitor of p38 mitogen-activated protein kinase (MAPK). Doramapimod is a potential agent for the treatment of inflammatory diseases. Doramapimod blocks baseline and bortezomib-triggered upregulation of p38 MAPK and Hsp27 phosphorylation leading to enhanced cytotoxicity and caspase activation.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
1mg $45.00
5mg $70.00
25mg $265.00
  Pack size Price(USD)
2mg $55.00
10mg $120.00
50mg $495.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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