D494423 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
0.5mg
$ 365.000.0
5mg
$ 2825.000.0
Exact Weight Packaging
$ 145.000.0
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D494423

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Product Description

Catalogue NumberD494423
Chemical NameDocetaxel-d5
Synonyms(αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy-d5)
Alternate CAS #148408-66-6-unlabelled
Molecular FormulaC₄₃H₄₈D₅NO₁₄
AppearanceWhite to Yellow Solid
Melting Point>155°C (dec.)
Molecular Weight812.91
Storage-20°C
SolubilityChloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA labelled semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic.
ReferencesRingel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)