D494422 Chemical Structure

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1mg
$ 365.000.0
10mg
$ 2825.000.0
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D494422

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Product Description

Catalogue NumberD494422
Chemical NameDocetaxel-d9
Synonyms(αR,βS)-β-[[(1,1-Dimethylethoxy-d9)carbonyl]amino]-α-hydroxybenzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)
CAS Number940867-25-4
Alternate CAS #148408-66-6
Molecular FormulaC₄₃H₄₄D₉NO₁₄
AppearanceWhite to Off-White Solid
Melting Point163-165°C (dec.)
Molecular Weight816.93
Storage-20°C
SolubilityChloroform (Sparingly), Methanol (Slightly)
Category Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA labelled semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic.
ReferencesRingel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)