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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 175.00 | 0.0 | |
| 10mg | $ 330.00 | 0.0 | |
| 25mg | $ 775.00 | 0.0 | |
| 50mg | $ 1505.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
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D479400
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Product Description
| Catalogue Number | D479400 |
| Chemical Name | 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin |
| Synonyms | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine rapamycin deriv. |
| CAS Number | 143030-02-8 |
| Molecular Formula | C57H93NO13Si |
| Appearance | White Solid |
| Molecular Weight | 1028.43 |
| Storage | -20°C Freezer |
| Solubility | Dichloromethane, Methanol |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. |