D473810 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 173.000.0
25mg
$ 385.000.0
50mg
$ 724.000.0
100mg
$ 1395.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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D473810

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Product Description

Catalogue NumberD473810
Chemical Name(4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone
CAS Number1478664-10-6
Molecular FormulaC₄₄H₅₂F₂N₂O₆Si
AppearanceWhite Solid
Molecular Weight770.98
SolubilityDCM
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3S,4S,3’S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.
Referencesvan Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)