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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
10mg | $ 173.00 | 0.0 | |
25mg | $ 385.00 | 0.0 | |
50mg | $ 724.00 | 0.0 | |
100mg | $ 1395.00 | 0.0 | |
Exact Weight Packaging | $ 145.00 | 0.0 | |
Total | $ 0.0 |
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D473810
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Product Description
Catalogue Number | D473810 |
Chemical Name | (4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone |
CAS Number | 1478664-10-6 |
Molecular Formula | C₄₄H₅₂F₂N₂O₆Si |
Appearance | White Solid |
Molecular Weight | 770.98 |
Solubility | DCM |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | (4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3S,4S,3’S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor. |
References | van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000) |