D461000 Chemical Structure

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Product Description

Catalogue NumberD461000
Chemical Name4-(N-1-Dimethylaminonaphthalene-5-sulfonylamino)phenyl Isothiocyanate
Synonyms5-(Dimethylamino)-N-(4-isothiocyanatophenyl)-1-naphthalenesulfonamide; DNSAPITC;
CAS Number102417-94-7
Molecular FormulaC₁₉H₁₇N₃O₂S₂
AppearancePale Yellow Green Solid
Melting Point125-132°C
Molecular Weight383.49
Storage-20°C, Inert atmosphere, Light sensitive
SolubilityAcetonitrile, DMSO, Methanol
StabilityLight Sensitive; Store at -20°C and Desicate.
Category Standards; Fluorescent Reagents;
ApplicationsA fluorescent PITC homologue Edman-type reagent with similar coupling efficiency and repetitive degradation yield to those of PITC. Naphthalene derivatives may be particularly useful for preparing fluorescent drug or ligand analogues that are expected to bind to hydrophobic sites in proteins or membranes. The lipophilicity of these reagents may also facilitate the labelling of sites within the membrane-spanning portions of cellular proteins.Fluorescence: max. Abs. l = 335nm, max. Em. l = 536nm (in methanol)
ReferencesGordon, E., et al.: Chem. Biol., 7, 9 (2000),