D455305 Chemical Structure

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25mg
$ 165.000.0
100mg
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250mg
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Exact Weight Packaging
$ 95.000.0
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D455305

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Product Description

Catalogue NumberD455305
Chemical NameN-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-4,5-dimethoxy-2-nitrobenzamide
CAS Number1024592-54-8
Molecular FormulaC₂₈H₃₁N₃O₇
AppearanceYellow Foam
Molecular Weight521.56
Category Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsN-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-4,5-dimethoxy-2-nitrobenzamide is an intermediate in the synthesis of Tariquidar (T007600), a P-glycoprotein drug efflux pump inhibitor that is potentially used in cancer patients.
ReferencesFox. E., et al.: Expert. Rev. Anticancer. Ther., 7, 447 (2007); Hernandez, D., et al.: Biochem. Pharmacol., 85, 21 (2013); Bauer, F., et al.: Euro. J. Pharmacol., 696, 18 (2012);