Catalogue number: D455190
Chemical name: 3,3’-Diindolylmethane
Synonyms: 3,3’-Methylenebis-1H-indole; 3,3’-Bisindolylmethane; 3,3’-Diindolylmethane; 3,3’-Methylenebis-1H-indole; Arundine; Bis(1H-indol-3-yl)methane 3,3’-Methylenediindole; Bis(3-indolyl)methane; HB 236; DIM;
CAS Number: 1968-05-4
Possible CAS #: NA
Molecular form.: C₁₇H₁₄N₂
Appearance: Off-White to Pale Beige Solid
Melting Point: 163-166°C (dec.)
Mol. Weight: 246.31
Storage: Refrigerator
Solubility: Chloroform (Slightly, Heated), Methanol (Slightly)
Stability: No Data Available
Category: Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 3,3’-Diindolylmethane is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines. 3,3’-Diindolylmethane is an antiproliferative and inducer of apoptosis; promotes proteasomal degradation of Cdc25C and Cdk1. Inhibits phosphorylation of EGFR and downstream activation of ERK.
Dangerous Goods Info: NA
Peer Review Product Citations:

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