D450648 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
25mg
$ 210.000.0
50mg
$ 330.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
  • Request another packsize ? Click here.
  • Inventory Status : Currently Back Ordered - Please Request Lead Time
  • Ships On :
D450648

Bulk Order Request for D450648

#Pack SizeUnitQuantity
1.
2.
3.
4.
5.

Product Description

Catalogue NumberD450648
Chemical NameDihydroethidium
SynonymsHydroethidine; PD-MY 003; 5-Ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine; (±)-5-Ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine
CAS Number104821-25-2
Molecular FormulaC₂₁H₂₁N₃
Molecular Weight315.41
Category Research Tools; Molecular Biology; Fluorescent Reagents; Dyes;
ApplicationsDihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites.
References1. Bucana, C.D., et al. 1990. Exp. Cell Res. 190: 69-75. PMID: 2387329 2. Rothe, G. and Valet, G. 1990. J. Leukoc. Biol. 47: 440-448. PMID: 2159514 3. Perticarari, S., et al. 1991. Cytometry. 12: 687-693. PMID: 1782835 4. Carter, W.O., et al. 1994. J. Leukoc. Biol. 55: 253-258. PMID: 8301222 5. Mancini, M., et al. 1997. J. Cell Biol. 138: 449-469. PMID: 9230085 6. Haugen, T.S., et al. 1999. Eur. Respir. J. 14: 1100-1105. PMID: 10596697