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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
25mg | $ 210.00 | 0.0 | |
50mg | $ 330.00 | 0.0 | |
Exact Weight Packaging | $ 95.00 | 0.0 | |
Total | $ 0.0 |
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D450648
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Product Description
Catalogue Number | D450648 |
Chemical Name | Dihydroethidium |
Synonyms | Hydroethidine; PD-MY 003; 5-Ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine; (±)-5-Ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine |
CAS Number | 104821-25-2 |
Molecular Formula | C₂₁H₂₁N₃ |
Molecular Weight | 315.41 |
Category | Research Tools; Molecular Biology; Fluorescent Reagents; Dyes; |
Applications | Dihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites. |
References | 1. Bucana, C.D., et al. 1990. Exp. Cell Res. 190: 69-75. PMID: 23873292. Rothe, G. and Valet, G. 1990. J. Leukoc. Biol. 47: 440-448. PMID: 21595143. Perticarari, S., et al. 1991. Cytometry. 12: 687-693. PMID: 17828354. Carter, W.O., et al. 1994. J. Leukoc. Biol. 55: 253-258. PMID: 83012225. Mancini, M., et al. 1997. J. Cell Biol. 138: 449-469. PMID: 92300856. Haugen, T.S., et al. 1999. Eur. Respir. J. 14: 1100-1105. PMID: 10596697 |