D448660 Chemical Structure

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D448660

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Product Description

Catalogue NumberD448660
Chemical Namerel-(1R,2S)-erythro-Dihydro Bupropion Maleate
Synonymsrel-(αR)-3-Chloro-α-[(1S)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol Maleate;rel- (1R,2S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-ol Maleate; rac-(1R,2S)-erythro-Dihydro Bupropion Maleate; racemic-(1R,2S)-erythro-Dihydro Bupropion Maleate
Alternate CAS #99102-04-2 free base
Molecular FormulaC₁₇H₂₄ClNO₅
AppearanceWhite Solid
Melting Point162-164°C
Molecular Weight357.83
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityChloroform, DMSO, Methanol
Category Research Tools; Chiral Molecules; Ephedrine; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
Applications(1R,2S)-erythro-Dihydro Bupropion Maleate is a metabolite of Bupropion (B689625), a selective inhibitor of dopamine uptake. An antidepressant of the aminoketone class; aid in smoking cessation.
ReferencesWriter, J.H., et. al.: Sci. Total Environ., 461 (2013)