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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 45.00 | 0.0 | |
| 5mg | $ 95.00 | 0.0 | |
| 10mg | $ 155.00 | 0.0 | |
| 25mg | $ 260.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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D447775
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Product Description
| Catalogue Number | D447775 |
| Chemical Name | 5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics) |
| Synonyms | 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-1,3,5-triazin-2(1H)-one; 2'-Deoxy-5,6-dihydro-5-azacytidine; KP 1212; 6-Amino-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1,3,5-triazin-2(1H)-one; 4-Amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,6-dihydro-1,3,5-triazin-2-one; |
| CAS Number | 114522-16-6 |
| Molecular Formula | C₈H₁₄N₄O₄ |
| Appearance | White to Off-White Solid |
| Melting Point | >210°C (dec.) |
| Molecular Weight | 230.22 |
| Storage | 4°C, Inert atmosphere |
| Solubility | DMSO (Slightly, Heated, Sonicated) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals; Environmental Standards, Mutagens and Metabolites; |
| Applications | 5,6-Dihydro-5-aza-2’-deoxycytidine is a selective mutagen that induces A-to-G and G-to-A mutations in the genome of replicating HIV. First-in-class lethal mutagen of HIV-1; Anti-HIV inhibitor. |
| References | Peng, C. S., et al.: Proc. Natl. Acad. Sci. U.S.A., 112, 3229-3234 (2015); Rawson, J. M., et al.: Bioorg. Med. Chem., 21, 7222-7228 (2013); Murakami, E., et al.: Antiviral Res., 67, 10-17 (2005) |