D447775 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 45.000.0
5mg
$ 95.000.0
10mg
$ 155.000.0
25mg
$ 260.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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D447775

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Product Description

Catalogue NumberD447775
Chemical Name5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)
Synonyms4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-1,3,5-triazin-2(1H)-one; 2'-Deoxy-5,6-dihydro-5-azacytidine; KP 1212; 6-Amino-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1,3,5-triazin-2(1H)-one; 4-Amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,6-dihydro-1,3,5-triazin-2-one;
CAS Number114522-16-6
Molecular FormulaC₈H₁₄N₄O₄
AppearanceWhite to Off-White Solid
Melting Point>210°C (dec.)
Molecular Weight230.22
Storage4°C, Inert atmosphere
SolubilityDMSO (Slightly, Heated, Sonicated)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals; Environmental Standards, Mutagens and Metabolites;
Applications5,6-Dihydro-5-aza-2’-deoxycytidine is a selective mutagen that induces A-to-G and G-to-A mutations in the genome of replicating HIV. First-in-class lethal mutagen of HIV-1; Anti-HIV inhibitor.
ReferencesPeng, C. S., et al.: Proc. Natl. Acad. Sci. U.S.A., 112, 3229-3234 (2015); Rawson, J. M., et al.: Bioorg. Med. Chem., 21, 7222-7228 (2013); Murakami, E., et al.: Antiviral Res., 67, 10-17 (2005)