D446905 Chemical Structure

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Product Description

Catalogue NumberD446905
Chemical Name2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-Isoindole-1-carboxamide
SynonymsNAV 26;
CAS Number1198160-14-3
Molecular FormulaC₂₂H₂₁F₃N₂O₄
Molecular Weight434.41
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-Isoindole-1-carboxamide also known as NAV 26, is a potent and state-dependant blocker of sodium gated voltage channels with application towards pain relief. Analgesic.
ReferencesMacsari, I. et al.: J. Med. Cem., 55, 6866 (2012);