D431690 Chemical Structure

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D431690

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Product Description

Catalogue NumberD431690
Chemical Name1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indole
Synonyms(2,3-Dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]methanone; GW 405833; L 768242
CAS Number180002-83-9
Molecular FormulaC₂₃H₂₄Cl₂N₂O₃
Molecular Weight447.35
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indole is a selective CB2 receptor partial agonist for both human and rat. The ligand-receptor binding event is able to trigger antihyperalgesic effects for neuropathic and inflammatory pain in rodent.
ReferencesValenzano, K. J. et al.: Neuropharmacol. 48, 658 (2005); Clayton, N. et al.: Pain 96, 253 (2002); Whiteside, G. T., et al.: Eur J Pharmacol. 528, 65 (2005)