N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant

Catalogue number: D297840
Chemical name: N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
Synonyms: Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)-1-iminoethyl)hydrazinecarboxylate;
Impurity:
CAS Number: 219821-37-1
Possible CAS #: NA
Molecular form.: C₂₄H₂₅F₇N₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 566.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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