TRC | Details of CAS = 15917-65-4, ChemicalName = N-Desmethyl Tamoxifen Hydrochloride, synonym = (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride;N-Demethyltamoxifen Hydrochloride;, MolFormula = C₂₅H₂₈ClNO

Catalogue Number:	D293900
Chemical Name:	N-Desmethyl Tamoxifen Hydrochloride
Synonyms:	(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride;N-Demethyltamoxifen Hydrochloride;
CAS Number:	15917-65-4
Alternate CAS #:	freebase: 31750-48-8
Molecular Formula:	C₂₅H₂₈ClNO
Appearance:	White to Off-White Solid
Melting Point:	225-227°C (dec.)
Molecular Weight:	393.95
Storage:	Amber Vial, -20°C Freezer
Solubility:	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Category:	Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point:	N/A
Applications:	A main metabolite of the anti-cancer drug Tamoxifen (T006000).
References:	Fabian, C., et al.: Biopharm. Drug Dispos., 2, 381 (1981), Jordan, V., et al.: Breast Cancer Res. Treat., 15, 125 (1990), Mandlekar, S., et al.: Cancer Res., 60, 6601 (2000), Lim, Y., et al.: Cancer Chemother. Pharmacol., 55, 471 (2005), Rouanet, P., et al.: J. Clin. Oncol., 2005, 23, 2980 (2005)

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MSDS:	D293900.pdf

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