D292172 Chemical Structure

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D292172

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Product Description

Catalogue NumberD292172
Chemical NameDesmethyl Sibutramine-d6, Hydrochloride
Synonyms1-(4-Chlorophenyl)-N-methyl-α-(2-methylpropyl)-cyclobutanemethanamine-d6 Hydrochloride;
CAS Number1189935-32-7
Alternate CAS #[84467-94-7] unlabelled; Free Base: 1190043-19-6
Molecular FormulaC₁₆H₁₉D₆Cl₂N
AppearanceWhite Solid
Melting Point>242ºC (dec.)
Molecular Weight308.32
Storage-20°C Freezer, Under Inert Atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
ApplicationsA Labelled metabolite of Sibutramine, a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
ReferencesHanotin, C., et al.: Int. J. Obesity, 22, 32 (1998), Woolard, J., et al.: J. Pharmacol. Exp. Ther., 308, 1102 (2004), Geranton, S., et al.: Neuropharmacol., 46, 511 (2004),