Descyclopropyl Abacavir

Catalogue number: D288865
Chemical name: Descyclopropyl Abacavir
Synonyms: (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentene-1-methanol; USP Abacavir Related Compound A; Abacavir EP Impurity C; Abacavir Related Compound A; Abacavir Impurities; Abacavir Intermediates
Impurity: Abacavir EP Impurity C; Abacavir USP Related Compound A ,
CAS Number: 124752-25-6
Possible CAS #: NA
Molecular form.: C₁₁H₁₄N₆O
Appearance: Off-White to Pale Yellow Solid
Melting Point: 177-179ºC
Mol. Weight: 246.27
Storage: -20˚C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Dangerous Goods Info: NA
References:

Peer Review Product Citations:
MSDS: D288865.pdf
Keywords: Buy 124752-25-6 | Purchase 124752-25-6 | Order 124752-25-6 | 124752-25-6 supplier | 124752-25-6 manufacturer | 124752-25-6 distributor | 124752-25-6 cost

Order Product

  Pack size Price(USD)
1mg $65.00
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5mg $150.00
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50mg $1200.00
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  Pack size Price(USD)
2mg $110.00
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10mg $285.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock



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