D286245 Chemical Structure

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500mg
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1g
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2.5g
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D286245

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Product Description

Catalogue NumberD286245
Chemical Name(+)-α-Methylbenzylamine (-)-2,2-Dimethylcyclopropanecarboxylate
CAS Number28624-56-8
Alternate CAS #28624-52-4 & 3886-69-9
Molecular FormulaC₆H₁₀O₂ • C₈H₁₁N
Molecular Weight114.14 + 121.18
Category Building Blocks; Chiral Molecules; Miscellaneous;
Applications(+)-α-Methylbenzylamine (-)-2,2-Dimethylcyclopropanecarboxylate is an intermediate in the synthesis of (R,R)-Cilastatin (C441120), which is a derivative of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
ReferencesFinlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),