D282105 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 85.000.0
25mg
$ 195.000.0
mg100
$ 360.000.0
250mg
$ 800.000.0
500mg
$ 1515.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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D282105

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Product Description

Catalogue NumberD282105
Chemical NameN-Desacryloyl N-(3-Acryloyl-propanoyl) Ibrutinib
Synonyms(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate;
Molecular FormulaC28H28N6O4
Molecular Weight512.56
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsN-Desacryloyl N-(3-Acryloyl-propanoyl) Ibrutinib is a impurity of Ibrutinib (I124970), which acts as a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
ReferencesMacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)